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JollyRX
9th Floor, Empire Heights Tower A, Shuraa Gold Business Centre , Business Bay Dubai, AE
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6256766d11023a0742162edc Jolvig (Vigabatrin Sachet 500mg) https://cdn1.storehippo.com/s/6052eead9e1cf8aa024c48c8/6256763c11023a0742162a99/webp/a90_9821-copy.JPG

Jolvig | Vigabatrin Sachet and Tablets | Sabril | Details,Costing & Pricing 

Jolvig Vigabatrin (VGB) is a recently-released antiepileptic drug that works by a clearly defined mechanism of action inhibition of GABA transaminase leading to an elevation of brain GABA concentration. It has proven to be particularly effective as an adjunct to complex, partially and secondarily generalized seizures in adults and children, as well as in epileptic spasms in both short and long-term controlled studies. Currently, the global experience includes more than 150,000 patients exposed to this drug. VGB has a good pharmacokinetic profile, has a long effective half-life, and can be administered once or twice daily because it has low protein binding and is excreted primarily unchanged by the kidney.

  • Infantile spasms:
    • 50 mg/kg/day given in 2 divided doses
    • Subsequent dosing can be titrated every 3 days at 25-50 mg/kg/day
    • Maximum: 150 mg/kg/day in 2 divided doses
  • Refractory complex partial seizures:
Adults: Permanent loss of vision, malaise, leaning, nystagmus, tremor, blurred vision, memory loss, weight gain, joint pain, impaired coordination and confusion. Pediatrics 10 to 16 years: weight gain, upper respiratory tract infection, tremor, malaise, aggression, diplopia.    
  • Epileptic spasms: somnolence, bronchitis, otitis media and acute otitis media.
  • Vigabatrin causes permanent bilateral concentric visual field constriction.The frequency and extent of vision loss in these patients is not well characterized, as it can be difficult to assess the vision of infants and children. For this reason, the risks described below are primarily based on the experience of adults.
  • Based upon grownup studies, 30 percentage or extra of sufferers may be affected, ranging in severity from moderate to severe, such as tunnel imaginative and prescient to inside 10 ranges of visible fixation, and might bring about disability. In a few cases, vigabatrin can also harm the valuable retina and might lower visible acuity.
  • The onset of imaginative and prescient loss from vigabatrin is unpredictable and might arise inside weeks of beginning a remedy or sooner, or at any time after beginning remedy, even after months or years
  • Symptoms of vision loss from vigabatrin are unlikely to be recognized by patients or caregivers before vision loss is severe. Mild vision loss that is often unrecognized by the patient or caregiver can still affect function.

Alternate Brand Names

JOLVIG, VIGANEXT, SABRIL  

Why did the doctor ask me to have my eyesight tested? Does JolVIG powder for oral solutions affect eyesight?

It is important to get your vision checked while taking JOLVIG Powder for Oral Solution because it can lead to loss of vision. Your doctor may have a vision test at the start of treatment, 4 weeks after treatment, every 3 months during treatment, and then for 3-6 months.

My child was first prescribed SABRIL tablets, but now it has been changed to JolVIG powder for oral solutions (sachets) Will this have a lessened effect?

No, your physician will modify the dose of JOLVIG Powder for Oral Solution primarily based totally in your child`s frame weight and age. This could have the identical impact because the Sabril tablet.

Does JOLVIG Powder for Oral Solution have psychiatric side effects? If yes, what are they?

Common psychiatric side effects of the JOLVIG Powder for Oral Solution include restlessness, aggression, nervousness, irritability, depression, thought disorders and paranoia (feeling unreasonably suspicious), and insomnia.These side effects can usually be remedied by reducing or gradually discontinuing the dose. Severe psychological disturbances (such as feeling elated or over-excited which causes unusual behavior and the person may feel detached from reality) are rare but may also occur.

What if someone accidentally swallows more than the recommended dose of JOLVIG Powder for Oral Solution?

If you are taking more than the recommended dose of JOLVIG powder as an oral solution, you should contact your doctor or go to a nearby hospital immediately. Possible symptoms of overdose include drowsiness or loss/depressed level of consciousness.

How much should I take JOLVIG powder as an oral solution? Can I stop taking it if I have no symptoms?

Your doctor will suggest the time required to take JOLVIG powder as an oral solution. However, do not stop taking JOLVIG powder as an oral solution. If you stop, your seizures may get worse. Consult your doctor if you face any issues with JOLVIG Powder for Oral Solution.

Does JolVIG powder for oral solutions affect memory and concentration?

Yes, JolVIG Powder for Oral Solution may also have an effect on reminiscence and awareness in a few people. There can be different elements which could make a contribution to reminiscence issues like depression, anxiety, sleep disturbance, and common seizures.

What if I forget to take JolVIG Powder for Oral Solution?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, just take one dose. Do not take a double dose to make up for the missed dose.

How should I take JolVIG Powder for Oral Solution when I cross time zones? How should I carry my medicine when I travel? Will I get JolVIG Powder for Oral Solution abroad?

It is important to take JolVIG Powder for Oral Solution at prescribed intervals. Plan ahead and ask your doctor to adapt to time zone changes. Carry JolVIG Powder for Oral Solution in its original packaging along with doctor’s prescription. JolVIG Powder for Oral Solution may be available abroad depending on your destination. But, it is advisable that you carry enough stock for yourself.
For more informations, visit-

Jolvig / Vigabatrin Sachet: Know the Uses, Benefits, Side Effects and Availability

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Jolvig (Vigabatrin Sachet 500mg)

Jolvig (Vigabatrin Sachet 500mg)


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Description of product

Jolvig | Vigabatrin Sachet and Tablets | Sabril | Details,Costing & Pricing 

Jolvig Vigabatrin (VGB) is a recently-released antiepileptic drug that works by a clearly defined mechanism of action inhibition of GABA transaminase leading to an elevation of brain GABA concentration. It has proven to be particularly effective as an adjunct to complex, partially and secondarily generalized seizures in adults and children, as well as in epileptic spasms in both short and long-term controlled studies. Currently, the global experience includes more than 150,000 patients exposed to this drug. VGB has a good pharmacokinetic profile, has a long effective half-life, and can be administered once or twice daily because it has low protein binding and is excreted primarily unchanged by the kidney.

  • Infantile spasms:
    • 50 mg/kg/day given in 2 divided doses
    • Subsequent dosing can be titrated every 3 days at 25-50 mg/kg/day
    • Maximum: 150 mg/kg/day in 2 divided doses
  • Refractory complex partial seizures:
Adults: Permanent loss of vision, malaise, leaning, nystagmus, tremor, blurred vision, memory loss, weight gain, joint pain, impaired coordination and confusion. Pediatrics 10 to 16 years: weight gain, upper respiratory tract infection, tremor, malaise, aggression, diplopia.    
  • Epileptic spasms: somnolence, bronchitis, otitis media and acute otitis media.
  • Vigabatrin causes permanent bilateral concentric visual field constriction.The frequency and extent of vision loss in these patients is not well characterized, as it can be difficult to assess the vision of infants and children. For this reason, the risks described below are primarily based on the experience of adults.
  • Based upon grownup studies, 30 percentage or extra of sufferers may be affected, ranging in severity from moderate to severe, such as tunnel imaginative and prescient to inside 10 ranges of visible fixation, and might bring about disability. In a few cases, vigabatrin can also harm the valuable retina and might lower visible acuity.
  • The onset of imaginative and prescient loss from vigabatrin is unpredictable and might arise inside weeks of beginning a remedy or sooner, or at any time after beginning remedy, even after months or years
  • Symptoms of vision loss from vigabatrin are unlikely to be recognized by patients or caregivers before vision loss is severe. Mild vision loss that is often unrecognized by the patient or caregiver can still affect function.

Alternate Brand Names

JOLVIG, VIGANEXT, SABRIL  

Why did the doctor ask me to have my eyesight tested? Does JolVIG powder for oral solutions affect eyesight?

It is important to get your vision checked while taking JOLVIG Powder for Oral Solution because it can lead to loss of vision. Your doctor may have a vision test at the start of treatment, 4 weeks after treatment, every 3 months during treatment, and then for 3-6 months.

My child was first prescribed SABRIL tablets, but now it has been changed to JolVIG powder for oral solutions (sachets) Will this have a lessened effect?

No, your physician will modify the dose of JOLVIG Powder for Oral Solution primarily based totally in your child`s frame weight and age. This could have the identical impact because the Sabril tablet.

Does JOLVIG Powder for Oral Solution have psychiatric side effects? If yes, what are they?

Common psychiatric side effects of the JOLVIG Powder for Oral Solution include restlessness, aggression, nervousness, irritability, depression, thought disorders and paranoia (feeling unreasonably suspicious), and insomnia.These side effects can usually be remedied by reducing or gradually discontinuing the dose. Severe psychological disturbances (such as feeling elated or over-excited which causes unusual behavior and the person may feel detached from reality) are rare but may also occur.

What if someone accidentally swallows more than the recommended dose of JOLVIG Powder for Oral Solution?

If you are taking more than the recommended dose of JOLVIG powder as an oral solution, you should contact your doctor or go to a nearby hospital immediately. Possible symptoms of overdose include drowsiness or loss/depressed level of consciousness.

How much should I take JOLVIG powder as an oral solution? Can I stop taking it if I have no symptoms?

Your doctor will suggest the time required to take JOLVIG powder as an oral solution. However, do not stop taking JOLVIG powder as an oral solution. If you stop, your seizures may get worse. Consult your doctor if you face any issues with JOLVIG Powder for Oral Solution.

Does JolVIG powder for oral solutions affect memory and concentration?

Yes, JolVIG Powder for Oral Solution may also have an effect on reminiscence and awareness in a few people. There can be different elements which could make a contribution to reminiscence issues like depression, anxiety, sleep disturbance, and common seizures.

What if I forget to take JolVIG Powder for Oral Solution?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, just take one dose. Do not take a double dose to make up for the missed dose.

How should I take JolVIG Powder for Oral Solution when I cross time zones? How should I carry my medicine when I travel? Will I get JolVIG Powder for Oral Solution abroad?

It is important to take JolVIG Powder for Oral Solution at prescribed intervals. Plan ahead and ask your doctor to adapt to time zone changes. Carry JolVIG Powder for Oral Solution in its original packaging along with doctor’s prescription. JolVIG Powder for Oral Solution may be available abroad depending on your destination. But, it is advisable that you carry enough stock for yourself.
For more informations, visit-

Jolvig / Vigabatrin Sachet: Know the Uses, Benefits, Side Effects and Availability

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