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CC-102, Link Road, Jawahar Nagar Jaipur, IN
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609506470b60a2463b26ced0 JOLAVI https://cdn1.storehippo.com/s/6052eead9e1cf8aa024c48c8/60950782dc8ab519b94d28b2/webp/jolavi-midodrine-2-5mg-tab-packshot.png

JOLAVI TABLET

DESCRIPTION

Jolavi Tablet is used to treat low blood pressure (hypotension). It is prescribed to patients who experience dizziness due to low blood pressure while standing up suddenly from sitting or lying position. This medicine causes tightening of blood vessels and results in elevating your blood pressure.

This medicine is usually prescribed to be taken during daytime when people stand most often. But, it should not be taken if you are going to lie down for a long time after the dose. You should always take this medicine as advised by the doctor and should never discontinue it without consulting the doctor. You should monitor your blood pressure regularly while taking this medicine.

Common side effects of this medicine include headache, nausea, rash, and difficulty in urination. Consult your doctor if these side effects bother you. It may also cause supine hypertension, it is increase in your blood pressure while lying down.

Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Your doctor may ask for monitoring of kidney and liver function before and during the treatment with this medicine.


USES OF JOLAVI TABLET

Jolavi tablet is used to treat low blood pressure.


BENEFITS OF JOLAVI TABLET

In Low blood pressure

Jolavi Tablet is used in adults and children to relieve low blood pressure that may occur due to sudden change in posture from lying to sitting or standing up, during an operation or after an injury. This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.


SIDE EFFECTS

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you are worried about them.

Common side effects of Jolavi

  • Headache
  • Nausea
  • Rash
  • Difficulty in urination

HOW TO USE JOLAVI TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jolavi Tablet may be taken with or without food, but it is better to take it at a fixed time. This medicine should be taken during daytime or when you have to stand for long durations. Avoid taking it when you have to lie down for long hours and do not discontinue taking it without doctor’s advice.


HOW JOLAVI TABLET WORKS

Jolavi Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.


SAFETY ADVISE

Alcohol

CONSULT YOUR DOCTOR

It is unknown whether it is safe to consume alcohol with Jolavi Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Jolavi Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Jolavi Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is unknown whether Jolavi Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Jolavi Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Jolavi Tablet in patients with liver disease. Please consult your doctor.


QUICK TIPS

  • Take Jolavi Tablet at least 4 hours before bedtime to avoid the risk of high blood pressure at night time. 
  • Monitor your blood pressure regularly while taking this medicine. 
  • Inform your doctor if you have a history of the prostate disorder or blood circulation problem. 
  • Inform your doctor immediately if you notice symptoms of chest pain, palpitations, headache, shortness of breath, and blurred vision.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

FAQs

Q. Does Jolavi Tablet raise blood pressure?

Yes, Jolavi Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day life and in people who could not be treated successfully with other therapies.

Q. Does Jolavi Tablet affect heart rate?

Jolavi Tablet may slow down the heart rate slightly. It should be used cautiously when using it with other medicines (beta blockers, digitalis, etc.) which can further slow down the heart rate. Patients should be monitored if they experience symptoms which are suggestive of slow heart rate.

Q. Can I lie down after taking Jolavi Tablet?

You should not lie down immediately after taking Jolavi Tablet because of the risk of supine hypertension (high blood pressure that occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. You can reduce the risk of supine hypertension occurring during the night by elevating the head.

Q. Does Jolavi Tablet work immediately?

Jolavi Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only; the effect persists for about 2-3 hours.

Q. How do I take Jolavi Tablet?

Jolavi Tablet should be taken exactly as directed by your doctor. Jolavi Tablet is taken orally with or without food. Swallow the tablet as a whole with a glass of water. Usually, it is advised to take the medicine three times a day (morning, midday, and late afternoon [before 6PM]) with a gap of at least 3 hours. Take the last daily dose of Jolavi Tablet before an evening meal and at least 4 hours before bedtime.

Q. Who should not take Jolavi Tablet?

Jolavi Tablet is not advised for patients having allergy to any component of the product, severe heart disease, unusually slow heart rate, high blood pressure, and conditions causing tightening of the arteries. Along with that, treatment with Jolavi Tablet should be avoided if the patient has enlarged prostate gland, urinary retention (when the bladder can’t empty properly), pheochromocytoma (tumour of the adrenal medulla), acute or severe kidney disease, overactive thyroid, poor vision as a result of diabetes, and narrow-angle glaucoma (elevated pressure in the eye).

Q. Is any monitoring required during Jolavi Tablet treatment?

You may need to check your blood pressure and get your kidney and liver function tests done before you start taking Jolavi Tablet. Once you begin the treatment, keep a constant track of your blood pressure and heart rate, especially after lying down.

Q. How will I know that I have developed supine hypertension?

Symptoms of supine hypertension include chest pain, palpitations, shortness of breath, headache, and blurred vision. If you develop these symptoms, tell your doctor immediately. The doctor may reduce the dose of Jolavi Tablet or may discontinue treatment if the symptoms persists.

Q. Can I take metoprolol with Jolavi Tablet?

Using Jolavi Tablet and metoprolol together can make your heart rate considerably slow. Hence, you need to be careful while using both together. If you experience slow pulse, dizziness and fainting, inform your doctor, as the dose of these medicines may need to be modified.


REFERENCES:

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
  2. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 139.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 915-16.
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
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Description of product

JOLAVI TABLET

DESCRIPTION

Jolavi Tablet is used to treat low blood pressure (hypotension). It is prescribed to patients who experience dizziness due to low blood pressure while standing up suddenly from sitting or lying position. This medicine causes tightening of blood vessels and results in elevating your blood pressure.

This medicine is usually prescribed to be taken during daytime when people stand most often. But, it should not be taken if you are going to lie down for a long time after the dose. You should always take this medicine as advised by the doctor and should never discontinue it without consulting the doctor. You should monitor your blood pressure regularly while taking this medicine.

Common side effects of this medicine include headache, nausea, rash, and difficulty in urination. Consult your doctor if these side effects bother you. It may also cause supine hypertension, it is increase in your blood pressure while lying down.

Before taking this medicine, it is better to let your doctor know if you are suffering from any kidney or liver disease. Also, pregnant women and breastfeeding mothers should consult doctor before taking it. You must inform doctor about all the other medicines that you are taking apart from this medicine. Your doctor may ask for monitoring of kidney and liver function before and during the treatment with this medicine.


USES OF JOLAVI TABLET

Jolavi tablet is used to treat low blood pressure.


BENEFITS OF JOLAVI TABLET

In Low blood pressure

Jolavi Tablet is used in adults and children to relieve low blood pressure that may occur due to sudden change in posture from lying to sitting or standing up, during an operation or after an injury. This medicine helps to bring back the blood pressure within normal range and therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.


SIDE EFFECTS

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you are worried about them.

Common side effects of Jolavi

  • Headache
  • Nausea
  • Rash
  • Difficulty in urination

HOW TO USE JOLAVI TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jolavi Tablet may be taken with or without food, but it is better to take it at a fixed time. This medicine should be taken during daytime or when you have to stand for long durations. Avoid taking it when you have to lie down for long hours and do not discontinue taking it without doctor’s advice.


HOW JOLAVI TABLET WORKS

Jolavi Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.


SAFETY ADVISE

Alcohol

CONSULT YOUR DOCTOR

It is unknown whether it is safe to consume alcohol with Jolavi Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Jolavi Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Jolavi Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

CONSULT YOUR DOCTOR

It is unknown whether Jolavi Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Jolavi Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Jolavi Tablet in patients with liver disease. Please consult your doctor.


QUICK TIPS

  • Take Jolavi Tablet at least 4 hours before bedtime to avoid the risk of high blood pressure at night time. 
  • Monitor your blood pressure regularly while taking this medicine. 
  • Inform your doctor if you have a history of the prostate disorder or blood circulation problem. 
  • Inform your doctor immediately if you notice symptoms of chest pain, palpitations, headache, shortness of breath, and blurred vision.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

FAQs

Q. Does Jolavi Tablet raise blood pressure?

Yes, Jolavi Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day life and in people who could not be treated successfully with other therapies.

Q. Does Jolavi Tablet affect heart rate?

Jolavi Tablet may slow down the heart rate slightly. It should be used cautiously when using it with other medicines (beta blockers, digitalis, etc.) which can further slow down the heart rate. Patients should be monitored if they experience symptoms which are suggestive of slow heart rate.

Q. Can I lie down after taking Jolavi Tablet?

You should not lie down immediately after taking Jolavi Tablet because of the risk of supine hypertension (high blood pressure that occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. You can reduce the risk of supine hypertension occurring during the night by elevating the head.

Q. Does Jolavi Tablet work immediately?

Jolavi Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only; the effect persists for about 2-3 hours.

Q. How do I take Jolavi Tablet?

Jolavi Tablet should be taken exactly as directed by your doctor. Jolavi Tablet is taken orally with or without food. Swallow the tablet as a whole with a glass of water. Usually, it is advised to take the medicine three times a day (morning, midday, and late afternoon [before 6PM]) with a gap of at least 3 hours. Take the last daily dose of Jolavi Tablet before an evening meal and at least 4 hours before bedtime.

Q. Who should not take Jolavi Tablet?

Jolavi Tablet is not advised for patients having allergy to any component of the product, severe heart disease, unusually slow heart rate, high blood pressure, and conditions causing tightening of the arteries. Along with that, treatment with Jolavi Tablet should be avoided if the patient has enlarged prostate gland, urinary retention (when the bladder can’t empty properly), pheochromocytoma (tumour of the adrenal medulla), acute or severe kidney disease, overactive thyroid, poor vision as a result of diabetes, and narrow-angle glaucoma (elevated pressure in the eye).

Q. Is any monitoring required during Jolavi Tablet treatment?

You may need to check your blood pressure and get your kidney and liver function tests done before you start taking Jolavi Tablet. Once you begin the treatment, keep a constant track of your blood pressure and heart rate, especially after lying down.

Q. How will I know that I have developed supine hypertension?

Symptoms of supine hypertension include chest pain, palpitations, shortness of breath, headache, and blurred vision. If you develop these symptoms, tell your doctor immediately. The doctor may reduce the dose of Jolavi Tablet or may discontinue treatment if the symptoms persists.

Q. Can I take metoprolol with Jolavi Tablet?

Using Jolavi Tablet and metoprolol together can make your heart rate considerably slow. Hence, you need to be careful while using both together. If you experience slow pulse, dizziness and fainting, inform your doctor, as the dose of these medicines may need to be modified.


REFERENCES:

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
  2. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 139.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 915-16.
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:

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