A tumor necrosis factor (TNF) blocker, such as Humira or adalimumab, reduces the effects of a chemical in the body that can induce inflammation. Many inflammatory disorders in adults are treated with adalimumab, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, plaque psoriasis, and hidradenitis suppurativa. Humira is also used to treat Crohn's disease, juvenile idiopathic arthritis, ulcerative colitis, and uveitis in adults and children.
Humira has an effect on the immune system. Adalimumab can reduce your immune system's ability to fight infections, making infections more likely. People taking this medicine have developed serious infections caused by viruses, fung,us, or bacteria. These infections have resulted in the deaths of several persons.
Tuberculosis is a serious infection (TB). Your doctor should test you for tuberculosis (TB) before starting and during Humira use.
Tell your doctor if you experience signs of infection including fever, chills, pains, weariness, cough, skin sores, diarrhoea, or burning when you urinate before or during Humira treatment.
You should not use Humira if you are allergic to adalimumab.
If you have signs of infection, such as fever, chills, sweats, muscle aches, weariness, cough, bloody mucus, skin sores, diarrhoea, burning when you urinate, or feeling continually exhausted, tell your doctor before starting this prescription.
Humira should not be given to a child younger than 2 years old (or 6 years old if treating Crohn's disease). Children using this medicine should be current on all childhood immunizations before starting treatment.
Tell your doctor if you have ever had:
tuberculosis (or if anyone in your household has tuberculosis);
a chronic infection;
hepatitis B (adalimumab can cause hepatitis B to come back or get worse);
any numbness or tingling, or a nerve-muscle disorder such as multiple sclerosis or Guillain-Barre syndrome;
an allergy to latex rubber;
if you are scheduled to have major surgery; or
if you have recently received or are scheduled to receive any vaccine.
Tell your doctor where you live and if you have travelled recently or plan to travel in the near future. You could become infected with illnesses that are common in particular parts of the world.
Humira has the potential to develop a lethal type of lymphoma (cancer) of the liver, spleen, and bone marrow. This has mostly happened in Crohn's disease or ulcerative colitis-affected teenagers and young men. Anyone with an inflammatory autoimmune condition, on the other hand, may be at a higher risk of lymphoma. Consult your doctor about your own risk.
It's uncertain whether this medicine may harm an unborn child. If you're expecting a child, tell your doctor. Ascertain that any doctor caring for your newborn is aware of your use of adalimumab while pregnant.
Breastfeeding a baby while using this medicine may not be safe. Inquire with your doctor about any potential dangers.
Use the medicine as soon as you remember, and then go back to your regular injection schedule. Do not use extra medicine to make up the missed dose.
Do not inject Humira into skin that is bruised, red, tender, or hard.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while using adalimumab. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), or zoster (shingles).
If you see any of the following indicators of an allergic response to Humira, get immediate medical attention: hives; breathing difficulties; swelling of the cheeks, lips, tongue, or throat