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9th Floor, Empire Heights Tower A, Shuraa Gold Business Centre , Business Bay 79998 Dubai AE
JollyRX
9th Floor, Empire Heights Tower A, Shuraa Gold Business Centre , Business Bay Dubai, AE
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61d2c74e5fc46cf93f5a39d5 EPHEDRINE 50 MG / ML 1 AMP https://cdn1.storehippo.com/s/6052eead9e1cf8aa024c48c8/61d2c7406b7424919c6fc177/webp/ephedrine-50-mg.jpg

Ephedrine 50 MG / ML 1 AMP

Ephedrine sulfate is a potent sympathomimetic that stimulates both α and β receptors and has clinical uses related to both effects. Its peripheral effects, partly due to the release of norepinephrine, simulate the response obtained when adrenergic nerves are stimulated. These include elevated blood pressure, myocardial irritation, arteriole stenosis, bronchial and gastrointestinal smooth muscle relaxation, and pupil dilation. In the bladder, detrusor muscle relaxation is not noticeable, but the trigone and bladder deltoid muscles become more tense. Ephedrine sulfate also has a powerful effect on the central nervous system. It stimulates the cerebral cortex and subcortical center and explains its use in narcolepsy. Cardiovascular responses reported in humans include moderate tachycardia, altered or increased stroke volume, increased cardiac output, fluctuating changes in peripheral resistance, and usually increased blood pressure. increase. The effects of ephedrine are more pronounced in the heart than in blood vessels. Ephedrine sulfate increases blood flow in the coronary arteries, brain, and muscles. In patients with myasthenia gravis, administration of ephedrine sulfate injection results in a real but modest increase in exercise intensity. The exact mechanism by which ephedrine sulfate affects skeletal muscle contraction is unknown.

Indications and uses

Ephedrine sulfate injection (USP) is indicated for the treatment of allergic diseases such as bronchial asthma. This drug has long been used as an antihypertensive drug, especially during spinal anesthesia, where hypotension is common. In Stokes-Adams syndrome with complete heart block, ephedrine has similar values ​​to ephedrine. It has been shown as a central nervous system stimulant for narcolepsy and depression. It is also used for myasthenia gravis.

Contraindications

Allergic reactions to ephedrine sulfate are rare. Hypersensitivity, if known, is a particular contraindication. Patients who are hypersensitive to other sympathomimetics may also be hypersensitive to ephedrine sulphate.

Prevention

Special care should be taken when administering ephedrine sulfate injection, USP to patients with general heart disease, angina, diabetes, hyperthyroidism, benign prostatic hyperplasia, or hypertension, and patients with digital disease. is needed. Prolonged use can cause anxiety-like syndromes. Resistance to ephedrine sulfate may develop, but discontinuation of the drug temporarily restores its original effect. Drug Interactions When ephedrine sulphate is used in combination with general anesthetics, especially cyclopropane or halogenated hydrocarbons or digitalis glycosides, these drugs can sensitize the myocardium to the effects of ephedrine sulphate, resulting in cardiac arrhythmia. May cause. Therapeutic doses of ephedrine sulfate may inhibit the antihypertensive effects of guanethidine, betanidine, and debrisokin by migrating adrenergic blockers from the site of action of sympathetic nerve cells. The effects on humans are seen as relative or complete blockade of antihypertensive drugs due to a sudden rise in blood pressure. The combination of ephedrine sulfate injection, USP, and oxytocin can cause severe hypotension. Monoamine oxidase inhibitors enhance the pressor effect of ephedrine sulphate and can lead to hypertensive crisis. Ephedrine sulfate injection, USP should not be given during or within 14 days after MAOI administration. Pregnancy Category C No reproductive testing of animals with ephedrine sulfate injection has been performed. USP Also, if a drug is given to a pregnant woman, it is unclear whether the drug can harm the fetus or give birth. Ephedrine sulfate injection, USP should not be given to pregnant women unless explicitly indicated. It is unclear how ephedrine sulfate injection (USP), when given to the mother immediately before or during work, can affect the growth and development of the newborn or subsequent child. Breast-feeding mother Ephedrine sulfate is excreted in breast milk. Use by mothers during breastfeeding is not recommended as the risk to the baby is higher than normal.

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EPHEDRINE 50 MG / ML 1 AMP


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Description of product

Ephedrine 50 MG / ML 1 AMP

Ephedrine sulfate is a potent sympathomimetic that stimulates both α and β receptors and has clinical uses related to both effects. Its peripheral effects, partly due to the release of norepinephrine, simulate the response obtained when adrenergic nerves are stimulated. These include elevated blood pressure, myocardial irritation, arteriole stenosis, bronchial and gastrointestinal smooth muscle relaxation, and pupil dilation. In the bladder, detrusor muscle relaxation is not noticeable, but the trigone and bladder deltoid muscles become more tense. Ephedrine sulfate also has a powerful effect on the central nervous system. It stimulates the cerebral cortex and subcortical center and explains its use in narcolepsy. Cardiovascular responses reported in humans include moderate tachycardia, altered or increased stroke volume, increased cardiac output, fluctuating changes in peripheral resistance, and usually increased blood pressure. increase. The effects of ephedrine are more pronounced in the heart than in blood vessels. Ephedrine sulfate increases blood flow in the coronary arteries, brain, and muscles. In patients with myasthenia gravis, administration of ephedrine sulfate injection results in a real but modest increase in exercise intensity. The exact mechanism by which ephedrine sulfate affects skeletal muscle contraction is unknown.

Indications and uses

Ephedrine sulfate injection (USP) is indicated for the treatment of allergic diseases such as bronchial asthma. This drug has long been used as an antihypertensive drug, especially during spinal anesthesia, where hypotension is common. In Stokes-Adams syndrome with complete heart block, ephedrine has similar values ​​to ephedrine. It has been shown as a central nervous system stimulant for narcolepsy and depression. It is also used for myasthenia gravis.

Contraindications

Allergic reactions to ephedrine sulfate are rare. Hypersensitivity, if known, is a particular contraindication. Patients who are hypersensitive to other sympathomimetics may also be hypersensitive to ephedrine sulphate.

Prevention

Special care should be taken when administering ephedrine sulfate injection, USP to patients with general heart disease, angina, diabetes, hyperthyroidism, benign prostatic hyperplasia, or hypertension, and patients with digital disease. is needed. Prolonged use can cause anxiety-like syndromes. Resistance to ephedrine sulfate may develop, but discontinuation of the drug temporarily restores its original effect. Drug Interactions When ephedrine sulphate is used in combination with general anesthetics, especially cyclopropane or halogenated hydrocarbons or digitalis glycosides, these drugs can sensitize the myocardium to the effects of ephedrine sulphate, resulting in cardiac arrhythmia. May cause. Therapeutic doses of ephedrine sulfate may inhibit the antihypertensive effects of guanethidine, betanidine, and debrisokin by migrating adrenergic blockers from the site of action of sympathetic nerve cells. The effects on humans are seen as relative or complete blockade of antihypertensive drugs due to a sudden rise in blood pressure. The combination of ephedrine sulfate injection, USP, and oxytocin can cause severe hypotension. Monoamine oxidase inhibitors enhance the pressor effect of ephedrine sulphate and can lead to hypertensive crisis. Ephedrine sulfate injection, USP should not be given during or within 14 days after MAOI administration. Pregnancy Category C No reproductive testing of animals with ephedrine sulfate injection has been performed. USP Also, if a drug is given to a pregnant woman, it is unclear whether the drug can harm the fetus or give birth. Ephedrine sulfate injection, USP should not be given to pregnant women unless explicitly indicated. It is unclear how ephedrine sulfate injection (USP), when given to the mother immediately before or during work, can affect the growth and development of the newborn or subsequent child. Breast-feeding mother Ephedrine sulfate is excreted in breast milk. Use by mothers during breastfeeding is not recommended as the risk to the baby is higher than normal.

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