Multiple Myeloma and Mantle Cell Lymphoma: Know Complete facts 

Multiple Myeloma and Mantel Cell Lymphoma are types of blood cancer, while multiple myeloma affects the bone marrow, and mantel cell lymphoma affects the white blood cells. Each of these blood cancer has different symptoms, however, their treatment remains to be the same, which includes a targeting therapy using Velcade.

In this article, we take you through some of the symptoms of Multiple myeloma and mantle cell lymphoma along with their treatment!

What are Multiple Myeloma and Mantle Cell Lymphoma?

Before we dive deeper into this article, let us understand what are these two types of blood cancers in detail - 

Multiple Myeloma 

It is a type of cancer of the blood which affects the part of the bone called the bone marrow. The bone marrow produces the cells that form the blood, including red blood cells, white blood cells, platelets, and plasma cells.

However, when one has multiple Myeloma, these myeloma cells multiply and can build up inside the bone marrow. This can prevent the bone marrow from making enough red blood cells which in turn impairs the body’s ability to fight infections.  Myeloma cells multiply and can build up in the bone marrow. When they do, these cells can prevent the bone marrow from making enough red blood cells and also impair the 

Mantle Cell Lymphoma

It is a type of cancer which affects the white blood cells called the lymphocytes. These white blood cells help fight infections and other diseases in the body and are found in the blood and lymphatic systems, such as bone marrow, spleen, and lymph nodes. However,  when lymphocytes become cancerous, they can aggressively multiply and spread across different parts of the body and form tumours. These tumours can further cause the lymph nodes to enlarge.

Symptoms of Multiple Myeloma and Mantle Cell Lymphoma

Now let us understand the symptoms of both these types of blood cancer in detail below - 

Multiple Myeloma Symptoms - 

• Anaemia
• Bone damage
• Increase in blood calcium
• Renal (kidney) problems

Mantle Cell Lymphoma Symptoms-

• Swollen lymph nodes
• Loss of appetite
• Weight loss
• Fever
• Night sweats
• Nausea
• Fullness or discomfort as a result of enlarged tonsils, liver, or spleen
• Pressure or pain in the lower back
• Anaemia
• Vomiting
• Indigestion
• Abdominal pain or bloating

Treatment of Multiple Myeloma and Mantle Cell Lymphoma

One of the most beneficial treatments for these two types of blood cancer is the targeted therapy, called Velcade. It is a type of medication that belongs to the class of medicines called proteasome inhibitors. It is an FDA-approved treatment of multiple myeloma and mantle cell lymphoma. Velcade, the generic brand name for which is Bortezomib, works by blocking or slowing down the action of proteasomes inside cells. 

The medication is usually given in two ways and strictly by a healthcare professional

• As an injection that is given intravenously, that is into your vein or,
• As subcutaneously, that is under the skin 

You can read about Bortether 2 mg injection uses, benefits and more here!

Key Takeaways

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